The article shows the experience of urboecologists and oncologists coworking to introduce new methods of detection and prevention of malignant neoplasms in Saratov on the basis of complex geoecological researches using GIS-technologies. Also the structure and content of cartographic databases of specialized medical and geographic GIS, which allows creating carcinogenic situation maps, making screening researches and developing recommendations for oncologists and other medical specialties on the basis of there are considered.